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Jared Lewis

University of Chicago
(773) 702-3546
New Approaches for C-H Bond Functionalization
New catalytic methods to functionalize C-H bonds continue to emerge at a rapid pace due to the potential improvements in both atom and step efficiency that these transformations could exhibit over traditional synthetic approaches. We are investigating the use of dual catalyst systems to enable remote functionalization of unactivated C-H bonds with regioselectivity imposed by supramolecular scaffolds. As part of this program, we are exploring the transmetallation of organic fragments between discrete late metal complexes and the compatibility of these relatively unexplored elementary reactions with various dual catalytic C-C bond-forming reactions, such as direct arylation and olefin hydroarylation. (Taken from Prof. Lewis' webpage)
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