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Matthew J Brady

University of Chicago
Biochemistry, Biology
Energy sensing by adipocytes: connections to diabetes and obesity
We have identified a novel phosphatase targeting protein that promotes glucose storage as glycogen. Through adenoviral mediated protein overexpression and generation of transgenic animals, we can modulate the storage of glucose as glycogen in adipocytes. The effects of shunting carbon storage from lipid to glycogen on energy sensing, cellular function and insulin signaling in fat cells is being investigated.
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